Mahmoud Elnaggar

Assistant Professor - College of Applied and Health Sciences

Contact Details
Name: Mahmoud Elnaggar
Job Title: Assistant Professor
College: College of Applied and Health Sciences
Email: mahmoud.elnaggar@asu.edu.om
Phone: +96897844140 Ext.
Contact Details

Dr. Mahmoud Elnaggar has been involved, throughout his career, in the study of Bovine/Ruminant Infectious Diseases, with an emphasis on Immunology, Microbiology, and Vaccine Development. Mahmoud started his career obtaining BVSc, MVSc and PhD in Veterinary Immunology from Alexandria University, Egypt, where he was successfully able to develop a cytokine flow cytometeric assay for quick and sensitive diagnosis of bovine tuberculosis. Mahmoud has then joined The Washington State University Monoclonal Antibody Center (WSUMAC), USA as a postdoctoral research associate during the period December 2014 – October 2019. In that role, Mahmoud made significant contributions to the development of monoclonal antibody reagents for ruminant species for use in the study of the immune responses to their infectious diseases. He was also heavily involved in developing platforms/assays to study the primary and recall responses and assess candidate vaccines to bovine pathogens, e.g. Mycobacterium avium subspecies paratuberculosis, Mycobacterium bovis and Theileria parva. During the period November 2019 – August 2020, Mahmoud joined The School of Biochemistry and Immunology at Trinity College Dublin, Ireland as a research fellow to advance the mission of Teagasc Bovine Immunology group to study the bovine T cells epigenomic changes associated with mycobacterial infections. In September 2020, Mahmoud returned back to Egypt to take up a Lecturer and then promoted to an Assistant Professor tenure in Veterinary Microbiology at Alexandria University. Currently, since September 2022, Mahmoud holds the position of an Assistant Professor in Veterinary Microbiology at The College of Applied and Health Sciences, A'Sharqiyah University, Sultanate of Oman. The long-term goal of Mahmoud’s career is to establish a multidisciplinary research program in Microbiology and Immunology of livestock infectious diseases, and use the derived information for the rational design of accurate diagnostics and efficacious vaccines for the prevention and control of livestock infectious diseases, including zoonotic infections, to support the global One Health Agenda.


Microbiology and Immunology of Livestock Infectious Diseases

Journal paper

Ex vivo Platforms to Study the Primary and Recall Immune Responses to Intracellular Mycobacterial Pathogens and Peptide-Based Vaccines

DOI/URL: https://doi.org/10.3389/fvets.2022.878347

Flow Cytometric Analysis of the Cytotoxic T-Cell Recall Response to Theileria parva in Cattle Following Vaccination by the Infection and Treatment Method

DOI/URL: https://doi.org/10.3390/vetsci8060114

Advances in Understanding of the Immune Response to Mycobacterial Pathogens and Vaccines through Use of Cattle and Mycobacterium avium subsp. paratuberculosis as a Prototypic Mycobacterial Pathogen

DOI/URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541111/

Isolation of canine adipose-derived mesenchymal stem cells from falciform tissue obtained via laparoscopic morcellation: A pilot study

DOI/URL: https://doi.org/10.1111/vsu.13267

Simultaneous cognate epitope recognition by bovine CD4 and CD8 T cells is essential for primary expansion of antigen-specific cytotoxic T-cells following ex vivo stimulation with a candidate Mycobacterium avium subsp. paratuberculosis peptide vaccine

DOI/URL: https://doi.org/10.1016/j.vaccine.2019.12.052

relA is Achilles' heel for mycobacterial pathogens as demonstrated with deletion mutants in Mycobacterium avium subsp. paratuberculosis and Mycobacterium bovis bacillus Calmette-Guérin (BCG)

DOI/URL: https://doi.org/10.1016/j.tube.2020.101904

Pattern of CD14, CD16, CD163 and CD172a expression on water buffalo (Bubalus bubalis) leukocytes

DOI/URL: https://doi.org/10.1016/j.vetimm.2019.03.010

A peptide-based vaccine for Mycobacterium avium subspecies paratuberculosis
DOI/URL: https://doi.org/10.1016/j.vaccine.2019.04.040

Capacity to Elicit Cytotoxic CD8 T Cell Activity Against Mycobacterium avium subsp. paratuberculosis Is Retained in a Vaccine Candidate 35 kDa Peptide Modified for Expression in Mammalian Cells

DOI/URL: https://doi.org/10.3389/fimmu.2019.02859

Characterization of αβ and γδ T cell subsets expressing IL-17A in ruminants and swine

DOI/URL: https://doi.org/10.1016/j.dci.2018.04.003